IN SILICO ASSESSMENT OF BIOCOMPATIBILITY AND TOXICITY: MOLECULAR DOCKING AND DYNAMICS SIMULATION OF PMMA-BASED DENTAL MATERIALS FOR INTERIM PROSTHETIC RESTORATIONS

In silico assessment of biocompatibility and toxicity: molecular docking and dynamics simulation of PMMA-based dental materials for interim prosthetic restorations

Abstract Aim: This study aimed to comprehensively assess the biocompatibility and toxicity profiles of poly(methyl methacrylate) (PMMA) and its monomeric unit, methyl methacrylate (MMA), crucial components in dental materials for interim prosthetic restorations.Methodology: Molecular docking was employed to predict the binding affinities, energetic

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Comparative bioassay of silver nanoparticles and malathion on infestation of red flour beetle, Tribolium castaneum

Abstract Background Insecticide resistance is the major sword stand threat in pest control management.Formulation with silver nanoparticle can be used as an alternative method to overcome these problems.Nanoparticles can provide a cheap and reliable source against Tribolium castaneum.The primary aim of our study is to compare the insecticidal effic

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The value of Life Sciences in an Integrated Curriculum: A Reflective Perspective of studying two Life Sciences Degrees a decade apart and the challenges faced in professional life

In a recent MedEdPublish article by Keenan and Jennings (2017), I was interested in why some Life Sciences are under-represented in the wider medical literature.The article states anatomy to be the dominant discipline within medical schools and describes a close link between anatomy and educational research with the presence of an "established medi

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Psychological Wellbeing and Healthy Aging: Focus on Telomeres

Stress and depression are known to modulate the aging process, and might also affect telomere biology.In fact, exposure to some biochemical pathways involved in stress-related depression may contribute to an ‘‘accelerated aging„ phenotype, as well as the incidence of age-related diseases, including metabolic disorders and dementia

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Live-cell imaging of septins and cell polarity proteins in the growing dikaryotic vegetative hypha of the model mushroom Coprinopsis cinerea

Abstract The developmental biology underlying the morphogenesis of mushrooms remains poorly understood despite the essential role of fungi in the terrestrial environment and global carbon cycle.The mushroom Coprinopsis cinerea is a leading model system for the molecular and cellular basis of fungal morphogenesis.The dikaryotic vegetative hyphae of

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